About us

The UCL Cancer Institute is the hub for cancer research at University College London, one of the World's leading universities. The Institute draws together over 400 talented scientists who are working together to translate research discoveries into developing kinder, more effective therapies for cancer patients. In particular, it fosters links between basic cancer researchers across Biomedicine and with the clinical activities of our four partner hospital trusts, known as UCL Partners (University College London Hospital NHS Foundation Trust, Great Ormond Street Hospital for Children NHS Trust, the Royal Free Hampstead NHS Trust, and Moorfields Eye Hospital NHS Foundation Trust), as well as the London School of Pharmacy and Cancer Research UK. The Institute has greater clinical links than any comparable centre in the UK, creating a unique opportunity for significant impact on the delivery of clinical service to cancer patients. The Cancer Institute includes the Cancer Research UK and UCL Cancer Trials Centre which is one of the largest cancer trials centres in the UK conducting multi-centre national and international phase III trials, feasibility studies and early phase I and II studies. Also embedded within the UCL Cancer Institute, the CRUK-UCL Centre provides essential infrastructure to support cancer research within UCL and is a major catalyst in the success of UCL in integrating translational and clinical cancer research with excellent basic science. Furthermore, the Institute offers educational programmes that reflect the depth and breadth of research expertise that include BSc Cancer Biomedicine, iBSc Oncology, MSc Cancer and PhD studies. Further Information about the UCL Cancer Institute can be found on our website https://www.ucl.ac.uk/cancer/

About the role

Applications are invited for a Research Technician to work in the Leukaemia Biology Research group led by Prof Marc Mansour. The position is funded by a CRUK Therapeutic Discovery Pilot award. The project aims to identify potentially targetable regions of c-MYC. It is estimated that dysregulation of MYC occurs in over 70% of all human cancers, making it one of the most enticing targets for therapeutic intervention in cancer. However, drug development has been severely impeded by uncertainty regarding the binding partners of MYC that are absolutely required for MYC oncogenic function, as well as a lack of crystal structure of the N-terminal domain. We have developed a novel library screening approach that has the potential to uncover MYC structure-function at unprecedented resolution, that can ultimately inform drug design. The post-holder will primarily be involved in developing and following up on hits that are identified on the MYC library screen, under the supervision of Dr Victor Llombart, senior post-doctoral researcher. The post is funded for 18 months in the first instance (with the possibility of extension if further funding is awarded). We will consider applications to work on a part-time, flexible and job share basis wherever possible.

About you

The post-holder is expected to have experience in core molecular biology techniques, including vector design, cloning and mutagenesis as well as cell culture and western blot analysis. The successful candidate must have a bachelor’s degree in biomedical science, molecular or cellular biology, or possess the equivalent experience. Master’s degree in Biological Sciences and sound understanding of statistics and their applicability to biomedical research are desirable but not essential.

What we offer

As well as the exciting opportunities this role presents we also offer some great benefits some of which are below: 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days) Defined benefit career average revalued earnings pension scheme (CARE) Cycle to work scheme and season ticket loan On-Site nursery On-site gym Enhanced maternity, paternity and adoption pay Employee assistance programme: Staff Support Service Discounted medical insurance

Our commitment to Equality, Diversity and Inclusion

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong. We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women. You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/